Estrace 0.5mg
Estrace 0.5mg is one of 3 strengths in which Estrace (Estradiol) is supplied. The full range is 0.5mg, 1mg, 2mg. This page covers what the 0.5mg strength is used for and how it fits into typical dosing.
Forms and dosages
Estrace is supplied as oral tablets in 0.5, 1 and 2mg strengths and as 0.01% vaginal cream. Menopausal HRT typically starts at the lowest effective dose — 0.5–1mg orally — and titrates based on symptom relief. Vaginal cream is applied 2–4g daily for two weeks then 1g 1–3 times weekly for maintenance. Women with an intact uterus require concomitant progesterone to prevent endometrial hyperplasia.
Indications
Estrace tablets are approved for moderate-to-severe vasomotor menopausal symptoms, prevention of post-menopausal osteoporosis (when other agents unsuitable), female hypogonadism, and as part of feminising hormone therapy. Vaginal cream is approved for moderate-to-severe symptomatic urogenital atrophy. Off-label use in transgender women under specialist supervision is widespread.
All strengths
Full profile →The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.