Cialis with the birth control pill
Many women of reproductive age take a combined or progestogen-only oral contraceptive while also using a chronic medication such as Cialis (Tadalafil). The combination is generally fine at 2.5mg, 5mg, 10mg, 20mg, but a small number of medications can reduce contraceptive efficacy meaningfully and need either a backup method or a switch.
How Cialis can affect contraceptive efficacy
Combined and progestogen-only contraceptives are metabolised through CYP3A4. Strong CYP3A4 inducers (some antiepileptics, rifampicin, St John's Wort) lower contraceptive plasma levels and reduce efficacy. Whether Tadalafil acts on CYP3A4 determines whether Cialis affects contraception. Most agents in Erectile Dysfunction (ED) have no clinically meaningful effect on the pill at 2.5mg, 5mg, 10mg, 20mg.
Practical guidance
According to the prescribing information for Tadalafil, women on hormonal contraception should review Cialis with the prescribing pharmacist or doctor. Where an interaction is documented, additional barrier contraception or switching to a non-oral method (IUD, implant) for the duration of Cialis therapy is the standard mitigation.
Frequently asked questions
Will Cialis make my pill less effective? ▾
Most Erectile Dysfunction (ED) medications at 2.5mg, 5mg, 10mg, 20mg do not affect oral contraceptive efficacy. The exceptions are CYP3A4-inducing drugs and a small number of others. The prescribing information for Tadalafil states whether the interaction is meaningful.
Do I need a backup contraceptive on Cialis? ▾
Backup contraception is needed only when there is a documented interaction between Cialis and the contraceptive method. For most users at 2.5mg, 5mg, 10mg, 20mg, no backup is required. The pharmacist confirms whether Tadalafil interacts with hormonal contraception.
More on Cialis
- With alcoholCialis and alcohol — is it safe to drink?
- With foodShould Cialis be taken with food?
- Side effectsCialis side effects: common, rare and warning signs
- Dosage guideCialis dosage guide: how much to take and when
- OnsetHow fast does Cialis start working?
- DurationHow long does Cialis last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.