Augmentin 875/125mg

Forms and dosages

Augmentin is administered orally with food to improve tolerability and clavulanate absorption. According to the prescribing information, the usual adult dose is 500/125mg every 8 hours or 875/125mg every 12 hours, depending on the indication. Paediatric dosing is weight-based using oral suspension. Dose reduction is required in significant renal impairment.

Indications

Augmentin is approved in adults and children for the treatment of respiratory tract infections including acute otitis media, sinusitis, community-acquired pneumonia and acute exacerbations of chronic bronchitis, urinary tract infections, dental infections, skin and soft tissue infections and intra-abdominal infections caused by beta-lactamase-producing bacteria. According to international guidelines, the addition of clavulanate extends the spectrum of amoxicillin to many resistant strains.