Priligy vs Caverject: side-by-side comparison
Priligy (Dapoxetine) and Caverject (Alprostadil) both belong to the Erectile Dysfunction (ED) class. They share clinical context but use different active ingredients. The choice between them depends on mechanism nuances, side-effect profile and individual response.
| Property | Priligy | Caverject |
|---|---|---|
| Active ingredient | Dapoxetine | Alprostadil |
| Manufacturer | Menarini | Pfizer |
| Class | Erectile Dysfunction (ED) | Erectile Dysfunction (ED) |
| Strengths | 30mg, 60mg | 10mcg, 20mcg, 40mcg |
| Forms | tablet | injection |
What's the same
Priligy and Caverject both belong to the Erectile Dysfunction (ED) class and are used for partially overlapping indications. The active ingredients — Dapoxetine vs Alprostadil — share the same therapeutic approach, so many safety and management points carry across both.
Key differences
Meaningful differences are in active ingredient (Dapoxetine vs Alprostadil), strengths (30mg, 60mg vs 10mcg, 20mcg, 40mcg), forms (tablet vs injection), and the mechanism, half-life and side-effect nuances that distinguish members of the class.
Mechanism and action
Priligy: Ejaculation is controlled by serotonergic pathways in the central nervous system. Caverject: Alprostadil binds prostaglandin E receptors on smooth muscle of the corpus cavernosum, triggering cAMP-mediated relaxation of cavernosal smooth muscle independent of the nitric oxide pathway used by PDE5 inhibitors.
When Priligy is preferred
Priligy is indicated for the on-demand treatment of premature ejaculation in adult men aged 18 to 64 years with a confirmed diagnosis.
When Caverject is preferred
Caverject is approved for erectile dysfunction of vasculogenic, neurogenic, psychogenic or mixed aetiology in adult men.
Frequently asked questions
Is Priligy or Caverject better? ▾
There is no single answer. Priligy and Caverject both belong to the Erectile Dysfunction (ED) class but differ in mechanism nuances, half-life and side-effect profile. Preference depends on the patient, the prescriber and prior response to other therapies.
Can I switch from Priligy to Caverject? ▾
Switching within the Erectile Dysfunction (ED) class is done under supervision, typically using equivalent doses and a follow-up period to confirm response and tolerance. It is not a self-directed decision.
Do Priligy and Caverject have the same side effects? ▾
They share many of the Erectile Dysfunction (ED) class side effects, with differences from mechanism and dose. Each medication's prescribing information lists specifics.
More Priligy comparisons
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.