Cialis vs Caverject: side-by-side comparison
Cialis (Tadalafil) and Caverject (Alprostadil) both belong to the Erectile Dysfunction (ED) class. They share clinical context but use different active ingredients. The choice between them depends on mechanism nuances, side-effect profile and individual response.
| Property | Cialis | Caverject |
|---|---|---|
| Active ingredient | Tadalafil | Alprostadil |
| Manufacturer | Eli Lilly | Pfizer |
| Class | Erectile Dysfunction (ED) | Erectile Dysfunction (ED) |
| Strengths | 2.5mg, 5mg, 10mg, 20mg | 10mcg, 20mcg, 40mcg |
| Forms | tablet | injection |
What's the same
Cialis and Caverject both belong to the Erectile Dysfunction (ED) class and are used for partially overlapping indications. The active ingredients — Tadalafil vs Alprostadil — share the same therapeutic approach, so many safety and management points carry across both.
Key differences
Meaningful differences are in active ingredient (Tadalafil vs Alprostadil), strengths (2.5mg, 5mg, 10mg, 20mg vs 10mcg, 20mcg, 40mcg), forms (tablet vs injection), and the mechanism, half-life and side-effect nuances that distinguish members of the class.
Mechanism and action
Cialis: During sexual stimulation, nitric oxide is released in the corpus cavernosum and activates an enzyme that produces cyclic GMP. Caverject: Alprostadil binds prostaglandin E receptors on smooth muscle of the corpus cavernosum, triggering cAMP-mediated relaxation of cavernosal smooth muscle independent of the nitric oxide pathway used by PDE5 inhibitors.
When Cialis is preferred
Cialis is indicated in adult men for the treatment of erectile dysfunction.
When Caverject is preferred
Caverject is approved for erectile dysfunction of vasculogenic, neurogenic, psychogenic or mixed aetiology in adult men.
Frequently asked questions
Is Cialis or Caverject better? ▾
There is no single answer. Cialis and Caverject both belong to the Erectile Dysfunction (ED) class but differ in mechanism nuances, half-life and side-effect profile. Preference depends on the patient, the prescriber and prior response to other therapies.
Can I switch from Cialis to Caverject? ▾
Switching within the Erectile Dysfunction (ED) class is done under supervision, typically using equivalent doses and a follow-up period to confirm response and tolerance. It is not a self-directed decision.
Do Cialis and Caverject have the same side effects? ▾
They share many of the Erectile Dysfunction (ED) class side effects, with differences from mechanism and dose. Each medication's prescribing information lists specifics.
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The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.