Cialis Super Active vs Stendra: side-by-side comparison
Cialis Super Active (Tadalafil) and Stendra (Avanafil) both belong to the Erectile Dysfunction (ED) class. They share clinical context but use different active ingredients. The choice between them depends on mechanism nuances, side-effect profile and individual response.
| Property | Cialis Super Active | Stendra |
|---|---|---|
| Active ingredient | Tadalafil | Avanafil |
| Manufacturer | Eli Lilly | Metuchen Pharmaceuticals |
| Class | Erectile Dysfunction (ED) | Erectile Dysfunction (ED) |
| Strengths | 20mg | 50mg, 100mg, 200mg |
| Forms | soft gelatin capsule | tablet |
What's the same
Cialis Super Active and Stendra both belong to the Erectile Dysfunction (ED) class and are used for partially overlapping indications. The active ingredients — Tadalafil vs Avanafil — share the same therapeutic approach, so many safety and management points carry across both.
Key differences
Meaningful differences are in active ingredient (Tadalafil vs Avanafil), strengths (20mg vs 50mg, 100mg, 200mg), forms (soft gelatin capsule vs tablet), and the mechanism, half-life and side-effect nuances that distinguish members of the class.
Mechanism and action
Cialis Super Active: Tadalafil inhibits PDE5 in penile tissue during sexual arousal, allowing cyclic GMP to accumulate, smooth muscle to relax and blood inflow to increase. Stendra: Avanafil selectively inhibits phosphodiesterase type 5 (PDE5) in the corpus cavernosum, increasing cGMP and enhancing nitric-oxide-mediated vasodilation in response to sexual stimulation.
When Cialis Super Active is preferred
Cialis Super Active is intended for adult men with erectile dysfunction.
When Stendra is preferred
Stendra is approved for erectile dysfunction in adult men.
Frequently asked questions
Is Cialis Super Active or Stendra better? ▾
There is no single answer. Cialis Super Active and Stendra both belong to the Erectile Dysfunction (ED) class but differ in mechanism nuances, half-life and side-effect profile. Preference depends on the patient, the prescriber and prior response to other therapies.
Can I switch from Cialis Super Active to Stendra? ▾
Switching within the Erectile Dysfunction (ED) class is done under supervision, typically using equivalent doses and a follow-up period to confirm response and tolerance. It is not a self-directed decision.
Do Cialis Super Active and Stendra have the same side effects? ▾
They share many of the Erectile Dysfunction (ED) class side effects, with differences from mechanism and dose. Each medication's prescribing information lists specifics.
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The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.