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Yaz vs Cymbalta: side-by-side comparison

Yaz (Drospirenone/Ethinylestradiol) 3mg/0.02mg tablet
Yaz
vs
Cymbalta (Duloxetine) 20mg capsule
Cymbalta

Yaz (Hormone und Empfängnisverhütung) and Cymbalta (Antidepressiva) belong to different therapeutic classes and are rarely interchangeable. This page compares the medications' purposes, mechanisms and the situations where each is used.

Property Yaz Cymbalta
Active ingredient Drospirenone Duloxetine
Manufacturer Bayer Eli Lilly
Class Hormone und Empfängnisverhütung Antidepressiva
Strengths 3mg/0.02mg 20mg, 30mg, 60mg
Forms tablet capsule

What's the same

Yaz and Cymbalta are used in very different patients, and the points in common are limited. The main shared element is that both meet regulatory standards for efficacy and safety and benefit from pharmacist oversight.

Key differences

Yaz belongs to Hormone und Empfängnisverhütung while Cymbalta belongs to Antidepressiva. Indications, mechanisms and target populations differ. The comparison is most useful when a clinician has mentioned both medications and the patient wants to understand where each fits.

Mechanism and action

Yaz: Yaz verhindert eine Schwangerschaft über drei Mechanismen: Ovulationssuppression (dominanter Effekt), Verdickung des Zervixschleims zur Behinderung der Spermienpassage und Veränderungen der endometrialen Rezeptivität. Cymbalta: Cymbalta hemmt die Wiederaufnahme von Serotonin und Noradrenalin an der Synapse.

When Yaz is preferred

Yaz ist zur Kontrazeption bei erwachsenen Frauen, die ein orales Kontrazeptivum wünschen, zur Behandlung der prämenstruellen dysphorischen Störung (PMDS) sowie zur Behandlung moderater Akne bei Frauen ab 14 Jahren, die zugleich eine Kontrazeption wünschen, zugelassen.

When Cymbalta is preferred

Cymbalta ist zur Behandlung der Major Depression, der generalisierten Angststörung, diabetischer peripherer neuropathischer Schmerzen, Fibromyalgie und chronischer muskuloskelettaler Schmerzen zugelassen.

Häufig gestellte Fragen

Is Yaz or Cymbalta better?

Yaz and Cymbalta are not interchangeable — they treat different conditions. Asking which is "better" is meaningful only when a clinician has weighed both for the same specific clinical scenario.

Can I switch from Yaz to Cymbalta?

Switching between Yaz and Cymbalta is rarely an appropriate decision since they belong to different classes and treat different conditions. The real question is usually whether the diagnosis calls for one medication or the other — which the prescriber resolves.

Do Yaz and Cymbalta have the same side effects?

No — they belong to different classes and have distinct side-effect profiles. Each medication has its own prescribing information.

More Yaz comparisons

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