Synthroid vs Cymbalta: side-by-side comparison
Synthroid (Hormone und Empfängnisverhütung) and Cymbalta (Antidepressiva) belong to different therapeutic classes and are rarely interchangeable. This page compares the medications' purposes, mechanisms and the situations where each is used.
| Property | Synthroid | Cymbalta |
|---|---|---|
| Active ingredient | Levothyroxine | Duloxetine |
| Manufacturer | AbbVie | Eli Lilly |
| Class | Hormone und Empfängnisverhütung | Antidepressiva |
| Strengths | 25mcg, 50mcg, 75mcg, 100mcg, 150mcg | 20mg, 30mg, 60mg |
| Forms | tablet | capsule |
What's the same
Synthroid and Cymbalta are used in very different patients, and the points in common are limited. The main shared element is that both meet regulatory standards for efficacy and safety and benefit from pharmacist oversight.
Key differences
Synthroid belongs to Hormone und Empfängnisverhütung while Cymbalta belongs to Antidepressiva. Indications, mechanisms and target populations differ. The comparison is most useful when a clinician has mentioned both medications and the patient wants to understand where each fits.
Mechanism and action
Synthroid: Levothyroxin ersetzt das defizitäre endogene Thyroxin, das in den Geweben durch Deiodinasen in das aktive Hormon Trijodthyronin (T3) umgewandelt wird. Cymbalta: Cymbalta hemmt die Wiederaufnahme von Serotonin und Noradrenalin an der Synapse.
When Synthroid is preferred
Synthroid ist zur Behandlung der Hypothyreose jeglicher Ursache (Hashimoto-Thyreoiditis, nach Thyreoidektomie, nach Radioiodtherapie, kongenital), bei Struma sowie zur TSH-Suppression nach differenziertem Schilddrüsenkarzinom zugelassen.
When Cymbalta is preferred
Cymbalta ist zur Behandlung der Major Depression, der generalisierten Angststörung, diabetischer peripherer neuropathischer Schmerzen, Fibromyalgie und chronischer muskuloskelettaler Schmerzen zugelassen.
Häufig gestellte Fragen
Is Synthroid or Cymbalta better? ▾
Synthroid and Cymbalta are not interchangeable — they treat different conditions. Asking which is "better" is meaningful only when a clinician has weighed both for the same specific clinical scenario.
Can I switch from Synthroid to Cymbalta? ▾
Switching between Synthroid and Cymbalta is rarely an appropriate decision since they belong to different classes and treat different conditions. The real question is usually whether the diagnosis calls for one medication or the other — which the prescriber resolves.
Do Synthroid and Cymbalta have the same side effects? ▾
No — they belong to different classes and have distinct side-effect profiles. Each medication has its own prescribing information.
More Synthroid comparisons
Die Informationen auf dieser Website dienen ausschließlich zu Referenz- und Bildungszwecken. Sie ersetzen nicht die Beratung durch qualifiziertes medizinisches Fachpersonal.