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Lexapro vs Celebrex: side-by-side comparison

Lexapro (Escitalopram) 5mg tablet
Lexapro
vs
Celebrex (Celecoxib) 50mg capsule
Celebrex

Lexapro (Antidepressiva) and Celebrex (Schmerzmedikamente) belong to different therapeutic classes and are rarely interchangeable. This page compares the medications' purposes, mechanisms and the situations where each is used.

Property Lexapro Celebrex
Active ingredient Escitalopram Celecoxib
Manufacturer Forest/Allergan Pfizer
Class Antidepressiva Schmerzmedikamente
Strengths 5mg, 10mg, 20mg 50mg, 100mg, 200mg, 400mg
Forms tablet capsule

What's the same

Lexapro and Celebrex are used in very different patients, and the points in common are limited. The main shared element is that both meet regulatory standards for efficacy and safety and benefit from pharmacist oversight.

Key differences

Lexapro belongs to Antidepressiva while Celebrex belongs to Schmerzmedikamente. Indications, mechanisms and target populations differ. The comparison is most useful when a clinician has mentioned both medications and the patient wants to understand where each fits.

Mechanism and action

Lexapro: Lexapro wirkt durch selektive Hemmung des Serotonin-Wiederaufnahmetransporters (SERT) an der Synapse und erhöht so die Verfügbarkeit von Serotonin für postsynaptische Rezeptoren. Celebrex: Celecoxib hemmt selektiv die COX-2, die induzierbare Cyclooxygenase-Isoform, die an Entzündungsorten hochreguliert ist, während die konstitutive COX-1, die die gastrale Mukosa und die Thrombozytenaggregation aufrechterhä…

When Lexapro is preferred

Lexapro ist bei Erwachsenen und Jugendlichen ab 12 Jahren (Depression) sowie bei Erwachsenen (generalisierte Angststörung) zur Behandlung von Major Depression und generalisierter Angststörung zugelassen.

When Celebrex is preferred

Celebrex ist bei Erwachsenen zugelassen für die Behandlung von Arthrose, rheumatoider Arthritis, juveniler idiopathischer Arthritis (in einigen Märkten), ankylosierender Spondylitis, primärer Dysmenorrhoe und akuten Schmerzen.

Häufig gestellte Fragen

Is Lexapro or Celebrex better?

Lexapro and Celebrex are not interchangeable — they treat different conditions. Asking which is "better" is meaningful only when a clinician has weighed both for the same specific clinical scenario.

Can I switch from Lexapro to Celebrex?

Switching between Lexapro and Celebrex is rarely an appropriate decision since they belong to different classes and treat different conditions. The real question is usually whether the diagnosis calls for one medication or the other — which the prescriber resolves.

Do Lexapro and Celebrex have the same side effects?

No — they belong to different classes and have distinct side-effect profiles. Each medication has its own prescribing information.

More Lexapro comparisons

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