Lexapro vs Ativan: side-by-side comparison
Lexapro (Antidepressiva) and Ativan (Angstlösende Medikamente) belong to different therapeutic classes and are rarely interchangeable. This page compares the medications' purposes, mechanisms and the situations where each is used.
| Property | Lexapro | Ativan |
|---|---|---|
| Active ingredient | Escitalopram | Lorazepam |
| Manufacturer | Forest/Allergan | Pfizer |
| Class | Antidepressiva | Angstlösende Medikamente |
| Strengths | 5mg, 10mg, 20mg | 0.5mg, 1mg, 2mg |
| Forms | tablet | tablet, oral concentrate, injection |
What's the same
Lexapro and Ativan are used in very different patients, and the points in common are limited. The main shared element is that both meet regulatory standards for efficacy and safety and benefit from pharmacist oversight.
Key differences
Lexapro belongs to Antidepressiva while Ativan belongs to Angstlösende Medikamente. Indications, mechanisms and target populations differ. The comparison is most useful when a clinician has mentioned both medications and the patient wants to understand where each fits.
Mechanism and action
Lexapro: Lexapro wirkt durch selektive Hemmung des Serotonin-Wiederaufnahmetransporters (SERT) an der Synapse und erhöht so die Verfügbarkeit von Serotonin für postsynaptische Rezeptoren. Ativan: Lorazepam bindet an die Benzodiazepin-Bindungsstelle des GABA-A-Rezeptors und verstärkt allosterisch die hemmende Chloridleitfähigkeit.
When Lexapro is preferred
Lexapro ist bei Erwachsenen und Jugendlichen ab 12 Jahren (Depression) sowie bei Erwachsenen (generalisierte Angststörung) zur Behandlung von Major Depression und generalisierter Angststörung zugelassen.
When Ativan is preferred
Ativan ist bei Erwachsenen zur Kurzzeitbehandlung von Angststörungen und angstbedingten Schlafstörungen zugelassen.
Häufig gestellte Fragen
Is Lexapro or Ativan better? ▾
Lexapro and Ativan are not interchangeable — they treat different conditions. Asking which is "better" is meaningful only when a clinician has weighed both for the same specific clinical scenario.
Can I switch from Lexapro to Ativan? ▾
Switching between Lexapro and Ativan is rarely an appropriate decision since they belong to different classes and treat different conditions. The real question is usually whether the diagnosis calls for one medication or the other — which the prescriber resolves.
Do Lexapro and Ativan have the same side effects? ▾
No — they belong to different classes and have distinct side-effect profiles. Each medication has its own prescribing information.
More Lexapro comparisons
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