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Celexa vs Neurontin: side-by-side comparison

Celexa (Citalopram) 10mg tablet
Celexa
vs
Neurontin (Gabapentin) 100mg capsule
Neurontin

Celexa (Antidepressiva) and Neurontin (Neurologische Arzneimittel) belong to different therapeutic classes and are rarely interchangeable. This page compares the medications' purposes, mechanisms and the situations where each is used.

Property Celexa Neurontin
Active ingredient Citalopram Gabapentin
Manufacturer Forest Laboratories / AbbVie Pfizer
Class Antidepressiva Neurologische Arzneimittel
Strengths 10mg, 20mg, 40mg 100mg, 300mg, 400mg, 600mg, 800mg
Forms tablet capsule, tablet, oral solution

What's the same

Celexa and Neurontin are used in very different patients, and the points in common are limited. The main shared element is that both meet regulatory standards for efficacy and safety and benefit from pharmacist oversight.

Key differences

Celexa belongs to Antidepressiva while Neurontin belongs to Neurologische Arzneimittel. Indications, mechanisms and target populations differ. The comparison is most useful when a clinician has mentioned both medications and the patient wants to understand where each fits.

Mechanism and action

Celexa: Citalopram hemmt selektiv den Serotonin-Reuptake-Transporter und erhöht damit die synaptische Serotoninverfügbarkeit, mit nur begrenzter Affinität zu Noradrenalin-Transportern oder anderen Rezeptoren. Neurontin: Gabapentin bindet an die Alpha-2-Delta-Hilfsuntereinheit spannungsabhängiger Calciumkanäle im zentralen Nervensystem und reduziert dadurch den präsynaptischen Calciumeinstrom sowie die Freisetzung exzitatorischer Neurotr…

When Celexa is preferred

Celexa ist zugelassen zur Behandlung der Major Depression.

When Neurontin is preferred

Neurontin ist bei Erwachsenen und Kindern ab drei Jahren zur Zusatztherapie fokaler Anfälle und bei Erwachsenen zur Behandlung der postherpetischen Neuralgie zugelassen.

Häufig gestellte Fragen

Is Celexa or Neurontin better?

Celexa and Neurontin are not interchangeable — they treat different conditions. Asking which is "better" is meaningful only when a clinician has weighed both for the same specific clinical scenario.

Can I switch from Celexa to Neurontin?

Switching between Celexa and Neurontin is rarely an appropriate decision since they belong to different classes and treat different conditions. The real question is usually whether the diagnosis calls for one medication or the other — which the prescriber resolves.

Do Celexa and Neurontin have the same side effects?

No — they belong to different classes and have distinct side-effect profiles. Each medication has its own prescribing information.

More Celexa comparisons

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