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Celexa vs Ativan: side-by-side comparison

Celexa (Citalopram) 10mg tablet
Celexa
vs
Ativan (Lorazepam) 0.5mg tablet
Ativan

Celexa (Antidepressiva) and Ativan (Angstlösende Medikamente) belong to different therapeutic classes and are rarely interchangeable. This page compares the medications' purposes, mechanisms and the situations where each is used.

Property Celexa Ativan
Active ingredient Citalopram Lorazepam
Manufacturer Forest Laboratories / AbbVie Pfizer
Class Antidepressiva Angstlösende Medikamente
Strengths 10mg, 20mg, 40mg 0.5mg, 1mg, 2mg
Forms tablet tablet, oral concentrate, injection

What's the same

Celexa and Ativan are used in very different patients, and the points in common are limited. The main shared element is that both meet regulatory standards for efficacy and safety and benefit from pharmacist oversight.

Key differences

Celexa belongs to Antidepressiva while Ativan belongs to Angstlösende Medikamente. Indications, mechanisms and target populations differ. The comparison is most useful when a clinician has mentioned both medications and the patient wants to understand where each fits.

Mechanism and action

Celexa: Citalopram hemmt selektiv den Serotonin-Reuptake-Transporter und erhöht damit die synaptische Serotoninverfügbarkeit, mit nur begrenzter Affinität zu Noradrenalin-Transportern oder anderen Rezeptoren. Ativan: Lorazepam bindet an die Benzodiazepin-Bindungsstelle des GABA-A-Rezeptors und verstärkt allosterisch die hemmende Chloridleitfähigkeit.

When Celexa is preferred

Celexa ist zugelassen zur Behandlung der Major Depression.

When Ativan is preferred

Ativan ist bei Erwachsenen zur Kurzzeitbehandlung von Angststörungen und angstbedingten Schlafstörungen zugelassen.

Häufig gestellte Fragen

Is Celexa or Ativan better?

Celexa and Ativan are not interchangeable — they treat different conditions. Asking which is "better" is meaningful only when a clinician has weighed both for the same specific clinical scenario.

Can I switch from Celexa to Ativan?

Switching between Celexa and Ativan is rarely an appropriate decision since they belong to different classes and treat different conditions. The real question is usually whether the diagnosis calls for one medication or the other — which the prescriber resolves.

Do Celexa and Ativan have the same side effects?

No — they belong to different classes and have distinct side-effect profiles. Each medication has its own prescribing information.

More Celexa comparisons

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