Aygestin vs Provera: side-by-side comparison
Aygestin (Norethindrone) and Provera (Medroxyprogesterone) both belong to the Sexuelle Gesundheit der Frau class. They share clinical context but use different active ingredients. The choice between them depends on mechanism nuances, side-effect profile and individual response.
| Property | Aygestin | Provera |
|---|---|---|
| Active ingredient | Norethindrone | Medroxyprogesterone |
| Manufacturer | Various generics | Pfizer |
| Class | Sexuelle Gesundheit der Frau | Sexuelle Gesundheit der Frau |
| Strengths | 5mg | 2.5mg, 5mg, 10mg |
| Forms | tablet | tablet |
What's the same
Aygestin and Provera both belong to the Sexuelle Gesundheit der Frau class and are used for partially overlapping indications. The active ingredients — Norethindrone vs Medroxyprogesterone — share the same therapeutic approach, so many safety and management points carry across both.
Key differences
Meaningful differences are in active ingredient (Norethindrone vs Medroxyprogesterone), strengths (5mg vs 2.5mg, 5mg, 10mg), forms (tablet vs tablet), and the mechanism, half-life and side-effect nuances that distinguish members of the class.
Mechanism and action
Aygestin: Norethisteron bindet an Progesteronrezeptoren und entfaltet gestagene Wirkungen: Verdickung des Zervixschleims, Suppression des LH-Peaks, Verdünnung des Endometriums und Reduktion der Aktivität endometrialer Implantate b… Provera: Medroxyprogesteronacetat bindet an Progesteronrezeptoren und entfaltet starke gestagene Wirkungen: Verdickung des Zervixschleims, Hemmung der Ovulation, Atrophie des Endometriums und Reduktion der endometrialen Prolifera…
When Aygestin is preferred
Aygestin ist zugelassen bei endometrioseassoziierten Schmerzen, abnormer uteriner Blutung infolge hormoneller Dysbalance und sekundärer Amenorrhö.
When Provera is preferred
Provera ist zugelassen bei Amenorrhoe, abnormalen uterinen Blutungen aufgrund hormoneller Dysbalance und zur Prävention der Endometriumhyperplasie bei postmenopausalen Frauen unter Östrogentherapie.
Häufig gestellte Fragen
Is Aygestin or Provera better? ▾
There is no single answer. Aygestin and Provera both belong to the Sexuelle Gesundheit der Frau class but differ in mechanism nuances, half-life and side-effect profile. Preference depends on the patient, the prescriber and prior response to other therapies.
Can I switch from Aygestin to Provera? ▾
Switching within the Sexuelle Gesundheit der Frau class is done under supervision, typically using equivalent doses and a follow-up period to confirm response and tolerance. It is not a self-directed decision.
Do Aygestin and Provera have the same side effects? ▾
They share many of the Sexuelle Gesundheit der Frau class side effects, with differences from mechanism and dose. Each medication's prescribing information lists specifics.
More Aygestin comparisons
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